About Us

Welcome to the Department of Biochemistry and Molecular Biophysics

It is my pleasure to welcome you to the webpage of the Department of Biochemistry and Molecular Biophysics. Members of our Department are located on three Columbia University Campuses: the Columbia University Medical Center (CUMC), the Zuckerman Mind Brain Behavior Institute on the new Manhattanville campus, and the Morningside campus.

The BMB faculty applies the full spectrum of contemporary biophysical, biochemical, molecular, cellular and genomic technologies to study fundamental biological mechanisms. Areas of research include structural and computational biology, molecular neuroscience, developmental biology, gene regulation and signal transduction, RNA biology, virology, adaptive immunity in CRISPR–Cas systems, molecular evolution, and systems biology.

Image of Tom Maniatis, PhD

The research contributions of our faculty have been recognized by many international prizes and awards, including three Nobel  Prize winners: Eric Kandel (Physiology, 2000) "for his discovery concerning signal transduction in the nervous system", Richard Axel (Physiology, 2004) “for his discovery of odorant receptors and the organization of the olfactory system",and Joachim Frank (Chemistry 2017) "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution".

Several members of our department are members of the U.S. National academy of Science: Richard Axel, Joachim Frank, Steven Goff, Iva Greenwald, Wayne Hendrickson, Barry Honig, Eric Kandel, Arthur Karlin, Tom Maniatis, David Shaw and Charles Zuker; and the U.S. National Academy of Medicine: Steven Goff, Eric Kandel, Tom Maniatis, and Charles Zuker.

Tom Maniatis, PhD

Isidore S. Edelman Professor of Biochemistry
Chair, Department of Biochemistry and Molecular Biophysics
Principal Investigator at Columbia's Zuckerman Institute